Monday, February 17, 2020

Patterns of Italian immigration Essay Example | Topics and Well Written Essays - 750 words

Patterns of Italian immigration - Essay Example In contrary, to the modern Italy primarily united states, immigration has characterized the whole development. Italian immigration the United States has been on the way out and the consistency of these new arrivals has significantly changed in the recent years. For the stabilization of Italy population, there was a continuous immigration from North Africa and Eastern Europe. The present Italian immigrants in America have a good education, driven by the career, and their primary focus is the preserving of their language and culture (Barkan 42). The difference that can be seen in the present and the early immigrants are that those who migrated in the last centuries were poor, no education and they lacked skills. Ignorance of the government to people’s interests and needs is the primary cause that led to the massive immigration of Italians to the United States having in mind that they will be served accordingly. Looking for an advanced better life within a free society that is pr otected by the constitution. The making of the individual rights to be a priority; was also another factor that let the Italians make a move to the new world. The immigration, on the other hand, was driven by the uniqueness of the American civilization features which distinguishes it from other European countries. Influence of the American natural environment and the American culture. The culture was attributed to two fundamental factor; the impulse and the inspirations, this compelled men and women to leave not only in European countries, but also across the Atlantic.

Monday, February 3, 2020

Surface modification to control stem cell differentiation in vitro Essay

Surface modification to control stem cell differentiation in vitro - Essay Example The stem cells within a developing embryo can differentiate into all sorts of specialized cells (known as pluripotent cells), while they can also sustain the normal turnover of revitalizing organs, such as skin, blood, or intestinal tissues (Keller, 1995). (National Institute of Health, 2001) It is getting more and more apparent that stem cells are extensively sensitive to their surroundings and react to prompts rendered by, hardness in two (2D) and three-dimensional (3D), chemistry, topography and culture. Surface modification involves changing the surface of an object by bringing chemical, biological or physical characteristics distinct from those detected originally on the surface of that object. In biomaterials, the surface modification performs a substantial role in ascertaining the consequence of the interactions of biological-materials. The surface of a material can be customized by using a particular modification in the surface of material to improve adhesion, cell interactio ns and biocompatibility. Accordingly surface modification is critical in the designing and development of new medical devices and biomaterials. The principle for the surface modification within the biomaterials is thus to continue the fundamental physical characteristics of a biomaterial while changing only the outmost surface to regulate the bio-interaction. In case such kind of surface modification is appropriately accomplished the functionality and mechanical properties of the device will remain unaffected, however, the bio-response associated to the device-tissue boundary will be modulated or improved. These surface modifications can be accomplished by utilizing mechanical, physiochemical or biological methods (Ratner, 2004). Objectives Stem cells are amazing cells, having both the abilities of differentiation to adult somatic cells and self-renewal in-vitro and in vivo. They possess various characteristics and advantages that can be coupled with the surface modification techniq ues to revolutionise healthcare applications and drug development. Stem cells provide a consistent and limitless furnish of physiologically applicable cells from formalized pathogen-free origins for practical applications like drug discovery, replacement therapies, toxicology studies and disease modelling (Roy, 2010). (National Institute of Health, 2001) Controlling Stem Cell Differentiation and Lineage Commitment The eventual purpose of bioengineering of stem cells is to become able to recognize and perhaps control the lineage commitment and differentiation of stem cells in vitro. Once this objective is attained, a huge number of therapeutic applications can be visualized. For instance one such application could be the production of different kinds of neurons in order to treat the injuries of spinal cord, Alzheimer’s disease or Parkinson’s disease. Similarly the development of the muscle cells of heart for patients who have suffered heart attacks can also be imagined. Moreover, the production of pancreatic cells relevant in the secretion of insulin-secreting can also be considered to treat those suffering from Diabetes (Type I), along with the production of stem cells of hair follicle to treat some specific kinds of baldness. Complete Organ Generation These bioengineering techniques could also